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Aripiprazole is an atypical antipsychotic. Its efficacy is believed to result from a combination of partial agonist activity at Dopamine D2 and Serotonin 5-HT 1A receptors, along with antagonist activity at Serotonin 5-HT 2A receptors. This mechanism contributes to improvements in schizophrenia, bipolar disorder, major depressive disorder, irritability in autistic disorder, and agitation in schizophrenia or bipolar disorder.
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✅ Description:
Aripra 10mg Tablet is an antipsychotic medication that contains Aripiprazole. It is primarily used for the treatment of mental health conditions like schizophrenia (characterized by unreal thoughts and behaviors) and bipolar disorder (marked by significant mood, energy, and cognitive changes). This medication helps to control symptoms but does not cure these disorders. Aripra works by altering the activity of specific chemicals in the brain.
- Aripra 10mg Tablet can be taken with or without food.
- The dose and duration of treatment will be determined by your doctor based on your clinical condition.
- To ensure a consistent level of the medicine in your body, try to take Aripra at the same time every day.
- Do not stop taking this medication suddenly without consulting your doctor, as this may result in withdrawal symptoms.
- Do not use Aripra 10mg Tablet if you are allergic to it.
- Inform your doctor about any existing medical conditions or other medications you are taking before starting treatment with this medicine. This will help in adjusting your dose to prevent undesired effects.
- Consult your doctor if you are pregnant or breastfeeding.
Safety Advices
Alcohol
UNSAFE
Consumption of alcohol is not recommended during treatment with Aripra 10 Tablet due to the increased risk of severe side effects such as dizziness, difficulty in concentration, and drowsiness.
Pregnancy
UNSAFE
Animal studies indicate that Aripra 10 Tablet may cause harm to your developing fetus during pregnancy. However, there are limited human data available. Hence, your doctor may weigh the risks and benefits of taking this medicine before prescribing it to you.
Breastfeeding
UNSAFE
Aripra 10 Tablet is not recommended for use while breastfeeding as it passes into the breast milk. Consult your doctor if you are breastfeeding.
CAUTION
Aripra 10 tablets may cause dizziness or drowsiness. Avoid driving vehicles or operating machines if you experience such symptoms during treatment with this medicine.
Kidney
CONSULT YOUR DOCTOR
Aripra 10 is safe to use in patients with kidney disease. No dose adjustment of Aripra 10 is recommended.
Liver
CONSULT YOUR DOCTOR
Aripra 10 is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aripra 10 may not be needed in these patients. Please consult your doctor.
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✔️ Aripra is indicated for the treatment of:
- Schizophrenia
- Bipolar disorder
- Adjunctive treatment of major depressive disorder
- Irritability associated with autistic disorder
- Agitation associated with schizophrenia or bipolar mania
✔️ How does Aripra work?
Aripra 10mg Tablet works by altering the activity of certain chemical substances in the brain.
✔️ Side Effects: Aripra 10
Common side effects include:
- Vomiting, nausea
- Akathisia, extrapyramidal disorder
- Somnolence, sedation, dizziness
- Insomnia, tremor, restlessness
- Fatigue, blurred vision, salivary hypersecretion
- Constipation, pyrexia, drooling, decreased appetite
✔️ Overdose Effects
- No fatalities have been reported with Aripra overdose up to 1080 mg. Symptoms may include nausea, vomiting, fatigue, diarrhea, and somnolence.
✔️ Dosage of Aripra 10
- Schizophrenia:
- Adults: Initial dose of 10-15 mg/day, with a recommended dose of 10-15 mg/day, and a maximum dose of 30 mg/day.
- Adolescents (ages 13-17 years): Initial dose of 2 mg/day, recommended dose of 10 mg/day, with a maximum dose of 30 mg/day.
- Bipolar Mania:
- Adults (monotherapy): Initial dose of 15 mg/day, recommended dose of 15 mg/day, and a maximum dose of 30 mg/day.
- Adults (adjunct to lithium or valproate): Initial dose of 10-15 mg/day, recommended dose of 15 mg/day, and a maximum dose of 30 mg/day.
- Pediatric patients (ages 10-17 years): Initial dose of 2 mg/day, recommended dose of 10 mg/day, and a maximum dose of 30 mg/day.
- Adjunct to Antidepressants for Major Depressive Disorder:
- Adults: Initial dose of 2-5 mg/day, recommended dose of 5-10 mg/day, and a maximum dose of 15 mg/day.
- Irritability in Autistic Disorder:
- Pediatric patients (ages 6-17 years): Initial dose of 2 mg/day, recommended dose of 5-10 mg/day, and a maximum dose of 15 mg/day.
✔️ Administration of Aripra 10
- Oral Formulations: Take once daily with or without food.
✔️ Interaction
- Caution is advised when combining Aripra with other centrally acting drugs or alcohol.
- Carbamazepine may lower blood levels of Aripra by increasing its clearance.
- Drugs like ketoconazole, quinidine, fluoxetine, or paroxetine may inhibit Aripra's elimination and increase its blood levels.
✔️ Contraindications
Known hypersensitivity to Aripiprazole.
✔️ Pregnancy & Lactation
- Pregnancy Category C: Aripiprazole should be avoided during pregnancy.
- It is recommended that women taking Aripiprazole should not breastfeed.
✔️ Precautions & Warnings
- Elderly Patients with Dementia-Related Psychosis: Increased risk of cerebrovascular adverse events, such as stroke or transient ischemic attack, including fatalities.
- Suicidality: Increased risk of suicidality in children, adolescents, and young adults with major depressive disorder.
- Tardive Dyskinesia: Discontinue if clinically appropriate.
- Metabolic Changes: Atypical antipsychotics may lead to hyperglycemia/diabetes, dyslipidemia, and weight gain.
- Orthostatic Hypotension: Use cautiously in patients with cardiovascular or cerebrovascular disease.
- Seizures/Convulsions: Use cautiously in patients with a history of seizures.
- Operating Machinery: Caution is advised when performing tasks requiring alertness.
✔️ Storage Conditions
Store below 30°C, away from light and moisture. Keep out of the reach of children
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